Article

Histone acetylation and chemoresistance in colorectal cancer : an opportunity for effective personalized treatment

2013-01-01

Abstract excerpt

Colorectal cancer (CRC) is the most common cause of deaths in the West. Despite many therapeutic opportunities, drug resistance or recurrence has significant rates among patients. Nearly 50% of CRC patients develop metastases. Therefore, sensitive biomarker and effective treatments with minimal toxicity are needed. Genetic and epigenetic alterations play major roles in initiation, development, and chemoresistance...

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Literature Corpus work: d45155ab-4eab-5cdf-9d6e-fb9b2add6f48
DOI: 10.25560/11581

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