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HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer

2020-11-19

Abstract excerpt

<h4>Background: </h4> Emerging evidence suggests that epithelial mesenchymal transition (EMT) and epigenetic mechanisms promote metastasis . Histone deacetylases (HDACs) and noncoding RNAs (ncRNAs) are important epigenetic regulators. Here, we elucidated a novel role of histone deacetylase 2 ( HDAC2 ) in regulating EMT and CRC metastasis via ncRNA. <h4>Methods: </h4>: The expression of HDACs in CRC was analyzed us...

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Literature Corpus work
6bb99f3e-2136-51c2-aaa2-d3ba68c0a9e4
DOI
10.21203/rs.3.rs-52947/v2
Open publication

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HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancerDOI 10.21203/rs.3.rs-52947/v2
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