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A phosphorylation signal activates genome-wide transcriptional control by BfmR, the global regulator of <i>Acinetobacter</i> resistance and virulence

2024-06-17

Abstract excerpt

<h4>ABSTRACT</h4> The nosocomial pathogen Acinetobacter baumannii is a major threat to human health. The sensor kinase-response regulator system, BfmS-BfmR, is essential to multidrug resistance and virulence in the bacterium and represents a potential antimicrobial target. Important questions remain about how the system controls resistance and pathogenesis. Although BfmR knockout alters expression of >1000 genes...

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Literature Corpus work
d44074ff-4d13-5e34-98e7-c80ebdd69003
DOI
10.1101/2024.06.16.599214
Open publication

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A phosphorylation signal activates genome-wide transcriptional control by BfmR, the global regulator of <i>Acinetobacter</i> resistance and virulenceDOI 10.1101/2024.06.16.599214
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