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Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A <i>Streptococcus</i>

2020-08-28

Abstract excerpt

<h4>Summary</h4> Catabolite control protein A (CcpA) is a master regulator of carbon source utilization and contributes to the virulence of numerous medically important Gram-positive bacteria. Most functional assessments of CcpA, including interaction with its key co-factor HPr, have been performed in non-pathogenic bacteria. In this study we aimed to identify the in vivo DNA binding profile of CcpA and assess th...

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Literature Corpus work
44699180-3023-53f6-b729-7ee797bb9c98
DOI
10.1101/2020.08.28.272682
Open publication

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Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A <i>Streptococcus</i>DOI 10.1101/2020.08.28.272682
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