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Phosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence

4 Oct 2023

Abstract excerpt

ABSTRACT Virulence effectors secreted by Mycobacterium tuberculosis ( Mtb ) help subvert host immune mechanisms and, therefore, are critical for establishing infection and pathogenesis. However, knowledge in terms of signaling mechanisms that modulate the secretion of virulence factors is sparse. We performed high-throughput secretome, phosphoproteome, and phospho-secretome analysis of Mtb . We combined the...

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PMID: 37791794
DOI: 10.1128/mbio.01232-23

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