Article

Genotyping complex structural variation at the malaria-associated human glycophorin locus using a PCR-based strategy

2019-09-05

Abstract excerpt

Structural variation in the human genome can affect risk of disease. An example is a complex structural variant of the human glycophorin gene cluster, called DUP4, which is associated with a clinically-significant level of protection against severe malaria. The human glycophorin gene cluster harbours at least 23 distinct structural variants and accurate genotyping of this complex structural variation remains a cha...

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Literature Corpus work: d4373029-c941-5933-93fb-e15cdb48d154
DOI: 10.1101/758334

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