Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay.

doi:10.1101/gr.3185605

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay.

Genome research - 1 Feb 2005

Hardenbol Paul, Yu Fuli, Belmont John, Mackenzie Jennifer, Bruckner Carsten, Brundage Tiffany, Boudreau Andrew, Chow Steve, Eberle Jim, Erbilgin Ayca, Falkowski Mat, Fitzgerald Ron, Ghose Sy, Iartchouk Oleg, Jain Maneesh, Karlin-Neumann George, Lu Xiuhua, Miao Xin, Moore Bridget, Moorhead Martin, Namsaraev Eugeni, Pasternak Shiran, Prakash Eunice, Tran Karen, Wang Zhiyong, Jones Hywel B, Davis Ronald W, Willis Thomas D, Gibbs Richard A

Abstract excerpt

Large-scale genetic studies are highly dependent on efficient and scalable multiplex SNP assays. In this study, we report the development of Molecular Inversion Probe technology with four-color, single array detection, applied to large-scale genotyping of up to 12,000 SNPs per reaction. While generating 38,429 SNP assays using this technology in a population of 30 trios from the Centre d'Etude Polymorphisme...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Inversion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cluster Analysis

Share to DNA Probes

Share to Gene Expression Profiling

Share to Genome, Human

Share to Molecular Probe Techniques

Share to Molecular Probes

Share to Research Design

Source

Open in PubMed Open full text

Identifiers

PMID: 15687290
DOI: 10.1101/gr.3185605
PMCID: PMC546528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay.PMID 15687290Read ↗

Molecular inversion probe assay.Semantic proximity Read ↗

Multiplexed genotyping with sequence-tagged molecular inversion probes.Semantic proximity Read ↗

Whole-genome genotyping with the single-base extension assay.Semantic proximity Read ↗

Ultrasensitive Detection of Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms.Semantic proximity Read ↗

Genotyping over 100,000 SNPs on a pair of oligonucleotide arrays.Semantic proximity Read ↗

Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing.Semantic proximity Read ↗

A genotyping system capable of simultaneously analyzing >1000 single nucleotide polymorphisms in a haploid genome.Semantic proximity Read ↗

Molecular inversion probe assay for allelic quantitation.Semantic proximity Read ↗

Assaying chromosomal inversions by single-molecule haplotyping.Semantic proximity Read ↗

Optimal genotype determination in highly multiplexed SNP data.Semantic proximity Read ↗

Two methods of whole-genome amplification enable accurate genotyping across a 2320-SNP linkage panel.Semantic proximity Read ↗

Advancing human genotyping: The Infinium HTS iSelect Custom microarray panel (Rita) development study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.