Article

LST1 Expression Correlates with Immune Infiltration and Predicts Poor Prognosis in Acute Myeloid Leukemia

2024-06-20

Abstract excerpt

<title>Abstract</title> <p>Clinical management of acute myeloid leukemia (AML) poses significant challenges due to its poor prognosis and heterogeneous nature. Discovering new biomarkers is crucial for improving risk assessment and customizing treatment approaches. While leukocyte-specific transcript 1 (LST1) is implicated in inflammation and immune regulation, its function in AML remains ambiguous. In this inves...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d40e1d6f-50bf-564e-a177-bfd4e0b5fae1
DOI: 10.21203/rs.3.rs-4515325/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

LST1 Expression Correlates with Immune Infiltration and Predicts Poor Prognosis in Acute Myeloid LeukemiaDOI 10.21203/rs.3.rs-4515325/v1Read

LST1 expression correlates with immune infiltration and predicts poor prognosis in acute myeloid leukemiaSemantic proximity Read

The cellular state space of AML unveils novel <i>NPM1</i> subtypes with distinct clinical outcomes and immune evasion propertiesSemantic proximity Read

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.Semantic proximity Read

Spatial multi-omics reveals targetable immunosuppressive macrophage T-cell interactions in human AML bone marrowSemantic proximity Read

Dynamics of Leukemic Blast and Immune Cell Populations in Acute Myeloid LeukemiaSemantic proximity Read

Multi-omics analysis identifies an M-MDSC-like immunosuppressive phenotype in lineage-switched AML with KMT2A rearrangementSemantic proximity Read

Transcriptomic analysis reveals proinflammatory signatures associated with acute myeloid leukemia progression.Semantic proximity Read

AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AMLSemantic proximity Read

Integrated Pan-Cancer Analysis Reveals Distinct Clinical, Genomic and Immunological Features of the LILRB Immune Checkpoint Family in Acute Myeloid LeukemiaSemantic proximity Read

RNA Sequencing Identifies WT1 Overexpression as a Predictor of Poor Outcomes in Acute Myeloid LeukemiaSemantic proximity Read

Pan-cancer analysis reveals distinct clinical, genomic, and immunological features of the LILRB immune checkpoint family in acute myeloid leukemiaSemantic proximity Read

Identification of STAT4 as a biomarker associated with tumor immunity and prognosis in acute myeloid leukemiaSemantic proximity Read