Article

Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models

2019-11-29

Abstract excerpt

<h4>ABSTRACT</h4> Human liver models that are 3-dimensional (3D) in architecture are proving to be indispensable for diverse applications, including compound metabolism and toxicity screening during preclinical drug development, to model human liver diseases for the discovery of novel therapeutics, and for cell-based therapies in the clinic; however, further development of such models is needed to maintain high l...

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Literature Corpus work: 8f4f8695-b767-5023-9baa-9f833d31e24d
DOI: 10.1101/857789

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