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The infection-tolerant mammalian reservoir of Lyme disease and other zoonoses broadly counters the inflammatory effects of endotoxin

2020-12-14

Abstract excerpt

<h4>ABSTRACT</h4> Animals that are competent natural reservoirs of zoonotic diseases commonly suffer little morbidity from the pathogens they persistently harbor. The mechanisms of this infection tolerance and the trade-off costs are poorly understood. We used exposure to a single dose of lipopolysaccharide (LPS) endotoxin as an experimental model of inflammation to compare the responses of the cricentine rodent...

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Literature Corpus work
d3ce0483-4dcf-5e66-8cbe-c0b3111d7a5c
DOI
10.1101/2020.12.13.422519
Open publication

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The infection-tolerant mammalian reservoir of Lyme disease and other zoonoses broadly counters the inflammatory effects of endotoxinDOI 10.1101/2020.12.13.422519
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