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Tissue specific dual RNA-seq defines host-parasite interplay in murine visceral leishmaniasis caused by <i>Leishmania donovani</i> and <i>Leishmania infantum</i>

2022-02-06

Abstract excerpt

Visceral leishmaniasis is associated with hepato-splenomegaly and altered immune and haematological parameters in both pre-clinical animal models and humans. We studied mouse experimental visceral leishmaniasis caused by Leishmania infantum and Leishmania donovani in BALB/c mice using dual RNA-seq to investigate the transcriptional response of host and parasite in liver and spleen. We identified only 4 species-s...

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Literature Corpus work
e115f9aa-e681-5891-a27b-c77026e88ba6
DOI
10.1101/2022.02.04.479211
Open publication

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Tissue specific dual RNA-seq defines host-parasite interplay in murine visceral leishmaniasis caused by <i>Leishmania donovani</i> and <i>Leishmania infantum</i>DOI 10.1101/2022.02.04.479211
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