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Dermal fibroblast cultures recapitulate differences between deermice and mice in responses to a Toll-like receptor agonist

2025-07-18

Abstract excerpt

The white-footed deermouse Peromyscus leucopus is a primary reservoir for the agents of Lyme disease and other zoonoses in North America and manifests infection tolerance for the bacteria, protozoa, and viruses it hosts. In previous in vivo studies P. leucopus and M. musculus differed in the degree of sickness and profiles of biomarkers after exposure to bacterial lipopolysaccharide, a TLR4 agonist. As an appro...

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Identifiers and source

Literature Corpus work
1dc0060f-e602-55a7-8cf0-d2422d47e094
DOI
10.1101/2025.07.16.665222
Open publication

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Dermal fibroblast cultures recapitulate differences between deermice and mice in responses to a Toll-like receptor agonistDOI 10.1101/2025.07.16.665222
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