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The white-footed deermouse, an infection-tolerant reservoir for several zoonotic agents, tempers interferon responses to endotoxin in comparison to the mouse and rat

2023-06-07

Abstract excerpt

The white-footed deermouse Peromyscus leucopus , a long-lived rodent, is a key reservoir for agents of several zoonoses, including Lyme disease. While persistently infected, this deermouse is without apparent disability or diminished fitness. For a model for inflammation elicited by various pathogens, the endotoxin lipopolysaccharide (LPS) was used to compare genome-wide transcription in blood by P. leucopus ,...

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Literature Corpus work
12d6d76f-768d-532d-9257-5a1c206b9f01
DOI
10.1101/2023.06.06.543964
Open publication

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The white-footed deermouse, an infection-tolerant reservoir for several zoonotic agents, tempers interferon responses to endotoxin in comparison to the mouse and ratDOI 10.1101/2023.06.06.543964
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