Article

STAT3 and GR cooperate to drive basal-like triple negative breast cancer gene expression and proliferation

2019-08-09

Abstract excerpt

Breast cancers can be divided into subtypes with different prognoses and treatment responses based on global gene expression differences. Luminal breast cancer gene expression and proliferation are driven by the transcription factors Estrogen Receptor α (ER), FOXA1 and GATA3. Targeting ER is the most effective therapy for treating luminal breast cancer because ER is the master regulator of the luminal gene express...

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Literature Corpus work: d3c265de-ea90-50db-aafe-c6be24d0669e
DOI: 10.1101/730606

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