Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucocorticoid Receptor (GR) Expression in Human Tumors: A Tissue Microarray Study on More than 14,000 Tumors

9 Jul 2025

Abstract excerpt

Background: The glucocorticoid receptor (GR) regulates the transcription of thousands of genes. In cancer, both oncogenic and tumor suppressive roles of GR have been proposed. Methods: A tissue microarray containing 18,527 samples from 147 tumor (sub-)types and 608 samples from 76 normal tissue types was analyzed for GR expression by immunohistochemistry. Results: GR positivity was found in 76.4% of 14,349...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to HER2/EGFR in Cancer Research
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40722755
DOI: 10.3390/biomedicines13071683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid Receptor (GR) Expression in Human Tumors: A Tissue Microarray Study on More than 14,000 TumorsPMID 40722755Read ↗

Duality of glucocorticoid action in cancer: tumor-suppressor or oncogene?Semantic proximity Read ↗

Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancerSemantic proximity Read ↗

Glucocorticoid receptor expression is associated with inferior overall survival independent of BRCA mutation status in ovarian cancerSemantic proximity Read ↗

Glucocorticoid receptor and RUNX transcription factors cooperatively drive CD8 T cell dysfunction in human cancerSemantic proximity Read ↗

Luminal breast cancer identity is determined by loss of glucocorticoid receptor activitySemantic proximity Read ↗

Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancerSemantic proximity Read ↗

Multiple Promoters Exist in the Human GR Gene, One of Which Is Activated by GlucocorticoidsSemantic proximity Read ↗

Glucocorticoid receptor collaborates with pioneer factors and AP-1 to execute genome-wide regulationSemantic proximity Read ↗

GR and ER Coactivation Alters the Expression of Differentiation Genes and Associates with Improved ER+ Breast Cancer OutcomeSemantic proximity Read ↗

Multiple Promoters Exist in the Human GR Gene, One of Which Is Activated by GlucocorticoidsSemantic proximity Read ↗

Expression and role of nuclear receptor coregulators in colorectal cancerSemantic proximity Read ↗

The origin and functions of multiple human glucocorticoid receptor isoforms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.