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Article

Antioxydation And Cell Migration Genes Are Identified as Potential Therapeutic Targets in Basal-Like and BRCA1 Mutated Breast Cancer Cell Lines.

International journal of medical sciences - 1 Jan 2018

Privat Maud, Rudewicz Justine, Sonnier Nicolas, Tamisier Christelle, Ponelle-Chachuat Flora, Bignon Yves-Jean

Abstract excerpt

Basal-like breast cancers are among the most aggressive cancers and effective targeted therapies are still missing. In order to identify new therapeutic targets, we performed Methyl-Seq and RNA-Seq of 10 breast cancer cell lines with different phenotypes. We confirmed that breast cancer subtypes cluster the RNA-Seq data but not the Methyl-Seq data. Basal-like tumor hypermethylated phenotype was not confirmed in...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epithelial-Mesenchymal Transition

Share to Gene Expression Regulation, Neoplastic

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Share to Sequence Analysis, RNA

Source

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Identifiers

PMID: 29333087
DOI: 10.7150/ijms.20508
PMCID: PMC5765739

Genes

BRCA1
ITGB1
ANXA1
MGST3
PFN1
SOD1
VIM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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