Article

Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated Schwann cell proliferation in human

2024-09-26

Abstract excerpt

<h4>Summary</h4> NF2-Related Schwannomatosis (previously referred to as Neurofibromatosis Type 2, or NF2) is a genetic-associated disease resulting from mutations in the gene, NF2 . NF2 encodes the merlin protein, which acts as a tumor suppressor. Bilateral vestibular schwannoma (VS) is a hallmark of NF2. Although the exactly molecular mechanism mediating NF2-driven schwannomatosis remain unclear, it is known t...

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Literature Corpus work: d3bc3e18-4e9a-5ec7-bc13-6a7e6f88399a
DOI: 10.1101/2024.09.24.614711

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