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A novel induced pluripotent stem cell model of Schwann cell differentiation reveals <i>NF2</i> - related gene regulatory networks of the extracellular matrix

2024-05-05

Abstract excerpt

Schwann cells are vital to development and maintenance of the peripheral nervous system and their dysfunction has been implicated in a range of neurological and neoplastic disorders, including NF2 -related schwannomatosis. We developed a novel human induced pluripotent stem cell (hiPSC) model to study Schwann cell differentiation in health and disease. We performed transcriptomic, immunofluorescence, and morpholo...

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Literature Corpus work
21c17e6a-101c-555e-a42c-30a57d96a285
DOI
10.1101/2024.05.02.591952
Open publication

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A novel induced pluripotent stem cell model of Schwann cell differentiation reveals <i>NF2</i> - related gene regulatory networks of the extracellular matrixDOI 10.1101/2024.05.02.591952
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