Article
NF2-Related Schwannomatosis (NF2): Molecular Insights and Therapeutic Avenues.
International journal of molecular sciences - 14 Jun 2024
Kim Bae-Hoon, Chung Yeon-Ho, Woo Tae-Gyun, Kang So-Mi, Park Soyoung, Kim Minju, Park Bum-Joon
Abstract excerpt
NF2-related schwannomatosis (NF2) is a genetic syndrome characterized by the growth of benign tumors in the nervous system, particularly bilateral vestibular schwannomas, meningiomas, and ependymomas. This review consolidates the current knowledge on NF2 syndrome, emphasizing the molecular pathology associated with the mutations in the gene of the same name, the NF2 gene, and the subsequent dysfunction of its...
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