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Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression

2018-08-14

Abstract excerpt

Injuries to the anterior cruciate ligament (ACL) often result in post-traumatic osteoarthritis (PTOA). To better understand the molecular mechanisms behind PTOA development following ACL injury, we profiled ACL injury-induced gene expression changes in knee joints of three mouse strains with varying susceptibility to OA: STR/ort (highly susceptible), C57BL/6 (moderately susceptible) and super-healer MRL/MpJ (not s...

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Literature Corpus work
d3ac04dc-223d-5e87-a912-84cd2622aa56
DOI
10.20944/preprints201808.0244.v1
Open publication

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Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and ProgressionDOI 10.20944/preprints201808.0244.v1
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