Article

LOXL2 alleviates post-traumatic knee osteoarthritis and pain

2025-05-13

Abstract excerpt

Cartilage has limited potential for self-regeneration, and damage can lead to structural, molecular, and functional aberrations, leading to osteoarthritis (OA). Traumatic knee injuries can also lead to cartilage degeneration and post-traumatic OA (PTOA). This study aimed to explore whether lysyl oxidase-like 2 (LOXL2) deletion promotes PTOA-induced transcriptional changes similar to those in human OA, as well as t...

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Literature Corpus work: 1b98d764-d29e-54dd-804f-3d5b70cbd56d
DOI: 10.1101/2025.05.12.653521

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