Article

Computational Translation of Mouse Models of Osteoarthritis Predicts Human Disease

2025-02-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Translation of biological insights from preclinical studies to human disease is a pressing challenge in biomedical research, including in osteoarthritis. Translatable Components Regression (TransComp-R) is a computational framework that has previously been used to synthesize preclinical and human OA data to identify biological pathways predictive of human disease conditions....

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Literature Corpus work: 4c31478e-6351-5fea-9133-c54f15ab92c7
DOI: 10.1101/2025.02.23.639777

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