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Article

Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis.

Arthritis and rheumatism - 1 Oct 2012

Poulet Blandine, Ulici Veronica, Stone Timothy C, Pead Matthew, Gburcik Valentina, Constantinou Eleni, Palmer Donald B, Beier Frank, Timmons James A, Pitsillides Andrew A

Abstract excerpt

OBJECTIVE: Chronological age is a powerful epidemiologic risk factor for osteoarthritis (OA), a multifactorial disease that is characterized by articular cartilage (AC) degradation. It is unclear from a molecular perspective how aging interacts with OA to produce this risk to AC integrity. To address this key question, we used in vivo time-course analysis of OA development and murine interstrain variability in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22833266
DOI: 10.1002/art.34572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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