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Investigating the Effects of Maltreatment and Acute Stress on the Concordance of Blood and DNA Methylation Methods of Estimating Immune Cell Proportions

2022-09-12

Abstract excerpt

<h4>Background: </h4> Immune cell proportions can be used to detect pathophysiological states and are also critical covariates in genomic analyses. The complete blood count (CBC) is the most common method of immune cell proportion estimation, but immune cell proportions can also be estimated using whole-genome DNA methylation (DNAm). Although the concordance of CBC and DNAm estimations has been validated in variou...

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Literature Corpus work
d3a9c21f-9e46-52b1-a5f7-0ba9717d20a2
DOI
10.21203/rs.3.rs-2043165/v1
Open publication

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Investigating the Effects of Maltreatment and Acute Stress on the Concordance of Blood and DNA Methylation Methods of Estimating Immune Cell ProportionsDOI 10.21203/rs.3.rs-2043165/v1
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