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Article

Validation of a DNA methylation reference panel for the estimation of nucleated cells types in cord blood

26 Sept 2016

Abstract excerpt

Cord blood is widely used as surrogate tissue in epigenome-wide association studies of prenatal conditions. Cell type composition variation across samples can be an important confounder of epigenome-wide association studies in blood that constitute a mixture of cells. We evaluated a newly developed cord blood reference panel to impute cell type composition from DNA methylation levels, including nucleated red...

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PMID: 27668573
DOI: 10.1080/15592294.2016.1233091

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