DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life.

doi:10.1038/s41467-024-52283-9

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Article

DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life.

Nature communications - 17 Sept 2024

Martino David, Kresoje Nina, Amenyogbe Nelly, Ben-Othman Rym, Cai Bing, Lo Mandy, Idoko Olubukola, Odumade Oludare A, Falsafi Reza, Blimkie Travis M, An Andy, Shannon Casey P, Montante Sebastiano, Dhillon Bhavjinder K, Diray-Arce Joann, Ozonoff Al, Smolen Kinga K, Brinkman Ryan R, McEnaney Kerry, Angelidou Asimenia, Richmond Peter, Tebbutt Scott J, Kampmann Beate, Levy Ofer, Hancock Robert E W, Lee Amy H Y, Kollmann Tobias R

Abstract excerpt

Understanding of newborn immune ontogeny in the first week of life will enable age-appropriate strategies for safeguarding vulnerable newborns against infectious diseases. Here we conducted an observational study exploring the immunological profile of infants longitudinally throughout their first week of life. Our Expanded Program on Immunization - Human Immunology Project Consortium (EPIC-HIPC) studies the...

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PMID: 39289350
DOI: 10.1038/s41467-024-52283-9
PMCID: PMC11408723

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