Article

Sex-specific hypothalamic axis disruption in the rNLS8 mouse model of amyotrophic lateral sclerosis (ALS)

2025-07-27

Abstract excerpt

Sex-related differences have gained increasing attention in recent years due to evidence of varying prevalence, pathophysiology, survival rates, and disease progression between males and females in amyotrophic lateral sclerosis (ALS). Differences in brain metabolism between sexes in ALS patients have also been reported; however, the specific molecular mechanisms remain poorly understood. As growing evidence suppor...

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Literature Corpus work: d3607a5a-fdd1-5706-8709-358b7bb0a586
DOI: 10.1101/2025.07.23.666305

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