Back to search

Article

A New Frontier in CWD Detection: Antemortem Plasma Biomarkers and Behavioral Profiling in Transgenic Mouse Models

2026-08-10

Abstract excerpt

Chronic Wasting Disease (CWD) is a fatal transmissible spongiform encephalopathy (TSE) that is confined to cervids (deer, moose, elk, and reindeer) but shares key properties with human neurodegenerative conditions such as Alzheimer’s, Parkinson’s, Huntington’s disease and frontal-temporal dementia. CWD and other TSEs are caused by the misfolded prion protein (PrP). Although the identification of diagnostic and pro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d35a0daa-597a-5e29-a5ff-e26a9f797d79
DOI
10.64898/2026.08.04.742870
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A New Frontier in CWD Detection: Antemortem Plasma Biomarkers and Behavioral Profiling in Transgenic Mouse ModelsDOI 10.64898/2026.08.04.742870
Clinical Use of Improved Diagnostic Testing for Detection of Prion Disease.Semantic proximity
Chronic wasting disease: an evolving prion disease of cervids.Semantic proximity
Regional patterns of neurodegeneration in a mouse model of proteinopathySemantic proximity
Evaluation of plasma tau and neurofilament light chain biomarkers in a 12-year clinical cohort of human prion diseasesSemantic proximity
Biomarker changes preceding symptom onset in genetic prion diseaseSemantic proximity
Sporadic human prion diseases: molecular insights and diagnosis.Semantic proximity
Utility of Animal Models to Understand Human Alzheimer’s Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of AnimalsSemantic proximity
Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse modelSemantic proximity
Pathological characterization of TgElk mice injected with brain homogenate from elk with chronic wasting disease.Semantic proximity
Transgenetic investigations of prion diseases of humans and animals.Semantic proximity
[Neuropathological diagnosis of prion disease].Semantic proximity
Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion diseaseSemantic proximity
Select a neighboring publication to make it the new centre.