Article

<i>DMRT1</i> is a testis determining gene in rabbits and is also essential for female fertility

2023-01-13

Abstract excerpt

DMRT1 is the testis-determining factor in several species of vertebrates, but its involvement in mammalian testes differentiation, where SRY is the testis-determining gene, remains ambiguous. So far, DMRT1 loss of function has been described in two mammalian species and induces different phenotypes: disorders of sex development (46, XY DSD) in men and male infertility in mice. We thus abolished DMRT1 expression b...

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Literature Corpus work: d2e0e3df-3950-5c1e-a5fb-4f775efe43cd
DOI: 10.1101/2023.01.13.523925

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