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Article

CRISPR/Cas9-mediated mosaic mutation of SRY gene induces hermaphroditism in rabbits.

Bioscience reports - 27 Apr 2018

Song Yuning, Xu Yuanyuan, Liang Mingming, Zhang Yuxin, Chen Mao, Deng Jichao, Li Zhanjun

Abstract excerpt

Hermaphroditism is a rare disorder that affects sexual development, resulting in individuals with both male and female sexual organs. Hermaphroditism is caused by anomalies in genes regulating sex determination, gonad development, or expression of hormones and their receptors during embryonic development during sexual differentiation. SRY is a sex-determination gene on the Y chromosome that is responsible for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29439141
DOI: 10.1042/BSR20171490
PMCID: PMC5861328

Genes

SRY

Provenance

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CRISPR/Cas9-mediated mosaic mutation of SRY gene induces hermaphroditism in rabbits.PMID 29439141Read ↗

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