Article

Generation and mutational analysis of a transgenic mouse model of human SRY

2021-03-04

Abstract excerpt

SRY is the Y-chromosomal gene that determines male sex development in humans and most other mammals. After three decades of study, we still lack a detailed understanding of which domains of the SRY protein are required to engage pathway of gene activity leading to testis development. Some insight has been gained from the study of genetic variations underlying differences/disorders of sex determination (DSD), but t...

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Literature Corpus work: a737f403-5261-5e33-8351-4c01150f6e77
DOI: 10.1101/2021.03.04.433906

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