Article

Lifespan analysis of repeat expression reveals age-dependent upregulation of HERV-K in the neurotypical human brain

2024-05-17

Abstract excerpt

DNA repetitive sequences (or repeats) comprise over 50% of the human genome and have a crucial regulatory role, specifically regulating transcription machinery. The human brain is the tissue with the highest detectable repeat expression and dysregulations on the repeat activity are related to several neurological and neurodegenerative disorders, as repeat-derived products can stimulate a pro-inflammatory response....

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Literature Corpus work: d2c6f9ec-5810-5019-9bfb-761b187bf380
DOI: 10.1101/2024.05.17.24307184

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Lifespan analysis of repeat expression reveals age-dependent upregulation of HERV-K in the neurotypical human brainDOI 10.1101/2024.05.17.24307184Read

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