Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Voltage-gated sodium channels, sodium transport and progression of solid tumours.

Current topics in membranes - 1 Jan 2023

Malcolm Jodie R, Sajjaboontawee Nattanan, Yerlikaya Serife, Plunkett-Jones Charlotte, Boxall Peter J, Brackenbury William J

Abstract excerpt

Sodium (Na+) concentration in solid tumours of different origin is highly dysregulated, and this corresponds to the aberrant expression of Na+ transporters. In particular, the α subunits of voltage gated Na+ channels (VGSCs) raise intracellular Na+ concentration ([Na+]i) in malignant cells, which influences the progression of solid tumours, predominantly driving cancer cells towards a more aggressive and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neoplasms
Share to Phenotype
Share to Sodium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Tumor Microenvironment

Share to Voltage-Gated Sodium Channels

Source

Identifiers

PMID: 38007270
DOI: 10.1016/bs.ctm.2023.09.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Voltage-gated sodium channels, sodium transport and progression of solid tumours.PMID 38007270Read ↗

A novel Na <sub>v</sub> 1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasisSemantic proximity Read ↗

Studies of ionic mechanisms associated with human cancersSemantic proximity Read ↗

The Emerging Role of Voltage-Gated Ion Channels in CancerSemantic proximity Read ↗

Pan-cancer analysis of the ion permeome reveals functional regulators of glioblastoma aggressionSemantic proximity Read ↗

Involvement of potassium channels in the progression of cancer to a more malignant phenotype.Semantic proximity Read ↗

Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.Semantic proximity Read ↗

THE ROLE OF POTASSIUM CHANNELS IN THE PATHOGENESIS OF GASTROINTESTINAL CANCERS AND THERAPEUTIC POTENTIALSemantic proximity Read ↗

Targeting the Voltage-Dependent K+ Channels Kv1.3 and Kv1.5 as Tumor Biomarkers for Cancer Detection and PreventionSemantic proximity Read ↗

Impact of intracellular ion channels on cancer development and progressionSemantic proximity Read ↗

New trends in glioma cancer therapy: Targeting Na+/H+ exchangersSemantic proximity Read ↗

Multidimensional pan cancer analysis of the sodium induced cell death gene TRPM4Semantic proximity Read ↗

Functional expression of voltage-gated sodium channels in human colorectal cancers in vitro : role in invasivenessSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.