Article

Boosting CAR-T cell therapy with CRISPR technology

2024-06-08

Abstract excerpt

Chimeric antigen receptor (CAR)-T cell therapy has made remarkable breakthroughs in treating cancers, especially hematologic malignancies, yet its broader application in cancer treatment is hindered by multiple challenges. Meanwhile, the development of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and its derived technologies has provided unprecedentedly efficient tools for genomic and cellula...

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Literature Corpus work: d2b3b549-017a-501d-bd67-dd2be324430c
DOI: 10.1016/j.hlife.2024.06.002

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