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Strengthening the CAR-T Cell Therapeutic Application using CRISPR/Cas9 Technology

2021-05-09

Abstract excerpt

Adoptive cell immunotherapy with chimeric antigen receptor (CAR) T cell has brought a revolutionary means of treatment for aggressive diseases such as hematologic malignancies and solid tumors. Over the last decade, FDA approved three types of CAR-T cells against CD19 hematologic malignancies, including Tisagenlecleucel (Kymriah), Axicabtagene ciloleucel (Yescarta), and Brexucabtagene autoleucel (Tecartus). Despit...

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Literature Corpus work
8b32f67e-0d4f-5089-9e19-ee9f0d819c68
DOI
10.22541/au.162058094.49226022/v1
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Strengthening the CAR-T Cell Therapeutic Application using CRISPR/Cas9 TechnologyDOI 10.22541/au.162058094.49226022/v1
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