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Multi-omics and spatial transcriptomics identify KCMF1 as an immune-metabolic driver of hepatocellular carcinoma progression

2026-01-12

Abstract excerpt

<title>Abstract</title> <p>Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, characterized by poor prognosis and limited treatment options. Ubiquitination, a key post-translational modification, plays crucial roles in cancer progression. However, the specific contribution of ubiquitination-associated genes to HCC remains largely unexplored. Public datasets from TCGA and GEO were analyzed to i...

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Literature Corpus work
d2acc21e-0acf-5179-884a-1d03f66eb6d5
DOI
10.21203/rs.3.rs-8472775/v1
Open publication

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Multi-omics and spatial transcriptomics identify KCMF1 as an immune-metabolic driver of hepatocellular carcinoma progressionDOI 10.21203/rs.3.rs-8472775/v1
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