Article

Chiral DNA sequences as commutable reference standards for clinical genomics

2018-08-31

Abstract excerpt

<h4>ABSTRACT</h4> Chirality is a geometric property describing any object that is inequivalent to a mirror image of itself. Due to its 5’-3’ directionality, a DNA sequence is distinct from a mirrored sequence arranged in reverse nucleotide order, and is therefore chiral. A given sequence and its opposing chiral partner sequence share many properties, such as nucleotide composition and sequence entropy. Here we de...

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Literature Corpus work: d27e513c-955e-590a-8bb8-52d723502c38
DOI: 10.1101/404285

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