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Article

Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of <i>Streptococcus pneumoniae</i>

2023-08-03

Abstract excerpt

<h4>ABSTRACT</h4> Previous virulence screens have indicated potential roles during Streptococcus pneumoniae infection for the one-carbon metabolism pathway component Fhs and proline synthesis mediated by ProABC. To define how these metabolic pathways affect S. pneumoniae virulence we have investigated phenotypes and transcription profiles of Δ fhs and Δ proABC strain mutants. S. pneumoniae capsular serotype...

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Literature Corpus work
d279fdbc-b563-5ee6-bb4f-6636b2ec645d
DOI
10.1101/2023.08.03.550501
Open publication

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Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of <i>Streptococcus pneumoniae</i>DOI 10.1101/2023.08.03.550501
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