Article
Exogenous proline promotes serum killing of Klebsiella pneumoniae
7 Aug 2025
Abstract excerpt
Klebsiella pneumoniae, a common pathogen responsible for bloodstream infections, can evade clearance by the complement-dependent killing in serum, known as serum resistance. However, strategy in managing K. pneumoniae serum resistance is still lacking. In this study, we employed metabolomics to identify the metabolic features of K. pneumoniae. We found that the pyruvate/TCA cycle and alanine, aspartate, and...
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