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Therapeutic immune cell engineering with an mRNA : AAV- <i>Sleeping Beauty</i> composite system

2023-03-15

Abstract excerpt

Adoptive cell therapy has shown clinical success in patients with hematological malignancies. Immune cell engineering is critical for production, research, and development of cell therapy; however, current approaches for generation of therapeutic immune cells face various limitations. Here, we establish a composite gene delivery system for the highly efficient engineering of therapeutic immune cells. This system,...

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Literature Corpus work
d2791911-b94e-524c-b6bb-2d844d3c7160
DOI
10.1101/2023.03.14.532651
Open publication

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Therapeutic immune cell engineering with an mRNA : AAV- <i>Sleeping Beauty</i> composite systemDOI 10.1101/2023.03.14.532651
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