Article

Single domain shark VNAR antibodies neutralize SARS-CoV-2 infection in vitro

2021-06-08

Abstract excerpt

Single domain shark VNAR antibodies can offer a viable alternative to conventional Ig-based monoclonal antibodies in treating COVID-19 disease during the current pandemic. Here we report the identification of neutralizing single domain VNAR antibodies selected against the SARS-CoV-2 spike protein derived from the Wuhan variant using phage display. We identified 56 unique binding clones that exhibited high affinity...

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Literature Corpus work: d253fbe3-32ac-5f76-a970-a73bcbe17117
DOI: 10.1101/2021.06.08.447530

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