Article

Development of a neutralization monoclonal antibody with a broad neutralizing effect against SARS-CoV-2 variants

2023-08-21

Abstract excerpt

<h4>Background: </h4> The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has challenged the effectiveness of current therapeutic regimens. Here, we aimed to develop a potent and broad SARS-CoV-2 antibody therapeutic by screening a scFv library with the spike protein receptor-binding domain (RBD) via phage display. Methods SKAI-DS84 was identified through phage display, and it u...

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Literature Corpus work: 57eba833-79d2-5bee-84e4-7a0e1678a76b
DOI: 10.21203/rs.3.rs-3261636/v1

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