Article

Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins

2022-02-01

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 infection or vaccination produces neutralizing antibody responses that contribute to better clinical outcomes. The receptor binding domain (RBD) and the N-terminal domain (NTD) of the spike trimer (S) constitute the two major neutralizing targets for the antibody system. Neutralizing antibodies targeting the RBD bind to several different sites on this domain. In contrast, most neutrali...

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Literature Corpus work: 64bb90e3-7020-5322-81cc-06f8fd393f41
DOI: 10.1101/2022.02.01.478695

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