Article

Vγ9+Vδ2+Tcell-mediated purging of <i>Listeria monocytogenes</i> -infected epithelial cells requires butyrophilin 3A genes

2023-06-07

Abstract excerpt

Intracellular bacteria produce antigens, which serve as potent activators of γδ T cells. Phosphoantigens are presented via a complex of Butyrophilins (BTN) to signal infection to human Vγ9+Vδ2+ T cells. Here, we established an in vitro system allowing for studies of Vγ9+Vδ2+ T cell activity in coculture with epithelial cells infected with the intracellular bacterial pathogen Listeria monocytogenes . We report tha...

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Literature Corpus work: d220e56b-1b2c-5e5d-ae60-4c1a204094f8
DOI: 10.1101/2023.06.07.544000

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Vγ9+Vδ2+Tcell-mediated purging of <i>Listeria monocytogenes</i> -infected epithelial cells requires butyrophilin 3A genesDOI 10.1101/2023.06.07.544000Read

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