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<i>Chlamydia</i> -induced <i>ex vivo</i> activation of B cells from mice, nonhuman primates, and humans produces large numbers of uniformly activated antigen presenting cells

2025-07-31

Abstract excerpt

<h4>ABSTRACT</h4> Chlamydia trachomatis ( Ct ) is a clinically important pathogen that causes ocular and genital infections. While genital Ct infection in women is typically persistent and asymptomatic, the host responses that dampen inflammation while gradually eradicating this bacterium are only partially defined. Herein, we show that Ct promotes human B cell activation via TLR2-mediated signaling of MyD88-d...

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Literature Corpus work
5964ba19-ad8c-5881-9000-8fa204b492c5
DOI
10.1101/2025.07.25.666778
Open publication

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<i>Chlamydia</i> -induced <i>ex vivo</i> activation of B cells from mice, nonhuman primates, and humans produces large numbers of uniformly activated antigen presenting cellsDOI 10.1101/2025.07.25.666778
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