Article

Characterisation of naturally occurring MERS-CoV Spike mutations and their impact on entry and neutralisation

2026-02-17

Abstract excerpt

In this study the phenotypic consequences of naturally occurring single nucleotide polymorphisms (SNPs) in the MERS-CoV Spike protein were investigated. The impact of Spike mutations on virus entry and neutralisation of contemporary MERS-CoV strains is not currently well understood. Naturally occurring mutations were identified by aligning 584 MERS-CoV Spike sequences from either human clinical isolates collected...

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Literature Corpus work: d2167c35-4ec8-59b0-8a9a-f2eca1ecd446
DOI: 10.64898/2026.02.17.706312

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