Article

Recurrent Emergence and Transmission of a SARS-CoV-2 Spike Deletion H69/V70

2021-02-05

Abstract excerpt

SARS-CoV-2 Spike amino acid replacements in the receptor binding domain (RBD) occur relatively frequently and some have a consequence for immune recognition. Here we report recurrent emergence and significant onward transmission of a six-nucleotide out of frame deletion in the S gene, which results in loss of two amino acids: H69 and V70. We show that 𝚫H69/V70 and other common NTD deletions occur at loop structur...

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Literature Corpus work: 34c60b65-7575-5e40-b045-2ba718e44ec4
DOI: 10.2139/ssrn.3780277

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