Article

BATF controls IFN I production via DC-SCRIPT in plasmacytoid dendritic cells

2024-01-14

Abstract excerpt

The basic leucine zipper ATF-like transcription factor (BATF) plays a pivotal role in coordinating various aspects of lymphoid cell biology, yet essential functions in dendritic cells (DCs) have not been reported. Here we demonstrate that BATF deficiency leads to increased interferon (IFN) I production in Toll-like receptor 9 (TLR9)-activated plasmacytoid dendritic cells (pDCs), while BATF overexpression has an in...

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Literature Corpus work: d2033f3d-8fef-5f25-9f44-401e5297e139
DOI: 10.1101/2024.01.11.574638

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