Article

Proteomic and single-cell transcriptomic dissection of human plasmacytoid dendritic cell response to influenza virus

2021-11-04

Abstract excerpt

Plasmacytoid dendritic cells [pDCs] represent a rare innate immune subset uniquely endowed with the capacity to produce substantial amounts of type-I interferons [IFN-I]. This function of pDCs is critical for effective antiviral defenses and has been implicated in autoimmunity. While IFN-I and select cytokines have been recognized as pDC secreted products, a comprehensive agnostic profiling of the pDC secretome in...

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Literature Corpus work: 0362750c-dcb8-578d-bafa-c2b2d6267595
DOI: 10.1101/2021.11.01.466839

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