Article

Investigating the role of CpG island DNA methylation at 3’UTRs in cancer

2024-10-21

Abstract excerpt

DNA methylation is one of the most important epigenetic processes that regulates gene expression. While the human genome is predominately methylated, CpG-rich regions known as CpG islands (CGIs) are unmethylated and are sites of transcriptional control. While the importance of CGI and DNA methylation at gene promoters is well understood, the significance of CGIs at 3’ untranslated regions (3’UTRs) remains largely...

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Literature Corpus work: d1fa38fe-6d61-5bc8-8f4c-f389f68ffc64
DOI: 10.1101/2024.10.18.619008

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